Maslinic Acid

Product Name: Maslinic acid
Botanical Source: Olea europaea L.
Part used: Fruit/Leaf
Specification: Maslinic acid 10%-98% HPLC
CAS No.: 4373-41-5

Molecular Formula: C30H48O4 
Molecular Weight: 472.7


Botanical source:Olea europaea L.

Synonyms:Crategolic Acid 2α-Hydroxyoleanoic Acid

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Product Introduction
Appearance: Fine White to Off White PowderParticle Size: 80 mesh
Loss on Drying: NMT 5.0%Ash Content: NMT 5.0%
Total Plate Count: <10,000cfu/gTotal Yeast & Mold: <1,000cfu/g
E. Coli: NegativeSalmonella: Negative



Heavy Metals
Arsenic (As): NMT 2ppmLead (Pb): NMT 2ppm
Cadmium (Cd): NMT 0.5ppmMercury(Hg): NMT 0.1ppm



Introduction

Maslinic acid is a pentacyclic triterpene found in a variety of natural sources, ranging from herbal remedies used in traditional Asian medicine to edible vegetables and fruits present in the Mediterranean diet. In recent years, several studies have proved that maslinic acid exerts a wide range of biological activities, i.e. antitumor, antidiabetic, antioxidant, cardioprotective, neuroprotective, antiparasitic and growth-stimulating. Experimental models used for the assessment of maslinic acid effects include established cell lines, which have been often used to elucidate the underlying mechanisms of action, and also animal models of different disorders, which have confirmed the effects of the triterpene in vivo.

Maslinic acid, a natural triterpene from Olea europaea L. This pentacyclic triterpene has an antiproliferative agent against Caco-2 cancer cells (EC50 = 15 µM), HT-29 human colon cancer cells (EC50 = 74 µM), 1321N1 astrocytoma cells (IC50 = 25 µM), and human leukemia (CCRF-CEM and CEM/ADR5000) cells (IC50 = 7 µM and 9 µM respectively).1,2,3,4 Maslinic acid · s antiproliferative activity likely comes from the induction of an oxidative apoptotic pathway, causing cell cycle and cytoskeleton alterations. Maslinic acid has been found to attenuate intracellular oxidative stress via inhibition of NO and H2O2 production and reduction of pro-inflammatory cytokine generation in murine macrophages.5 Recently maslinic acid has been found to inhibit the spread of the HIV virus by inhibiting the replication of a primary HIV-1 isolate as well as decreased the cytopathic effect and p24 antigen levels in MT2 cells.6


Application

Anti-oxidant 

An anti-inflammatory

Anti-microbial 

Anti-viral activities

Providing significant natural defense against colon-cancer

Restrain the conglomeration of blood platelet

As a dietary supplement to promote muscle growth

Reducing blood fat and pressure.

Be beneficial for diabetes

Inhibiting the spread of the HIV virus


Shipment Details
1. Packing: Packed in fiber drum, LDPE bag inside. Net weight: 25kgs/drum; 
2. Storage: Keep tightly sealed, store away from moisture, strong heat and sunlight;
3. Lead time: 7-10days after order confirmed;
4. Shelf Life: 2 years if sealed and stored in the recommended conditions;