Camptothecin (CPT) is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I (topo I). It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs. CPT showed remarkable anticancer activity in preliminaryclinical trials but also low solubility and (high) adverse drug reaction. Because of these disadvantages synthetic and medicinal chemists have developed numerous syntheses of Camptothecin and various derivatives to increase the benefits of the chemical, with good results. Two CPT analogues have been approved and are used in  cancerchemotherapy today, topotecan and irinotecan.

1. Anti-tumor: Camptothecin and its derivatives are unique in their ability to inhibit DNA Topoisomerase I, by stabilizing a covalent reaction intermediate termed the cleavable complex which ultimately causes tumor cell death.

2. Anti-virus, immunosuppressive & the process of changing the skin epidermal keratinocytes;

1. Packing: Packed in fiber drum, LDPE bag inside. Net weight: 25kgs/drum; 
2. Storage: Keep tightly sealed, store away from moisture, strong heat and sunlight;
3. Lead time: Usually 7-10days after order confirmed;
4. Shelf Life: 2 years if sealed and stored in the recommended conditions;