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Nicotinamide Riboside

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Abstract

Nicotinamide Riboside

Other Names: 1-(β-D-Ribofuranosyl)nicotinamide; N-Ribosylnicotinamide

CAS No.: 1341-23-7

Molecular Formula: C11H15N2O5+

Molecular Weight: 255.25

Appearance: liquid



Function:

Nicotinamide riboside is a pyridine-nucleoside precursor to vitamin B3 andnicotinamide adenine dinucleotide. Nicotinamide riboside is produced by yeast and some mammals.

Nicotinamide riboside is a supplement that's only recently become available on the market. It is a safe supplement for athletes and hard-trainers everywhere. A 2013 review notes nicotinamide riboside has potential to increase insulin sensitivity, exercise endurance, and act as a nootropic.

The effects of nicotinamide riboside (NR) on insulin sensitivity, mitochondrial biogenesis and improving sirtuin function are truly unique. NR is the first molecule to possess an enviable triple action: anti-ageing, slimming, energising, and improves insulin sensitivity.


For slimming

At present, researchers are still continuing their studies for using nicotinamide riboside as a nutritional supplement to fight obesity and other metabolic disorders. It helps the body burn more calories naturally, as NAD+ is a vital co-substrate of sirtuin enzymes. This clearly demonstrates that supplementing with NR offers the health benefits of following a low-calorie diet and taking regular exercise, without having to do either, and is thus particularly recommended for those who are overweight.


The hope for Alzheimer’s

Nicotinamide riboside supplementation could therefore benefit Alzheimer’s patients by improving cognitive function and synaptic plasticity, and to some degree, by preventing production of toxic beta-amyloid plaques in the brain.


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