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Theanine

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Abstract:

L-Theanine

Common Name: Suntheanine.

Green Tea Extract

Botanical Source: Camellia sinensis O. Ktze.

Part Used: Leaf

CAS No.: 3081-61-6

Specification: L-Theanine 20% ~ 98% 


Description:

L-theanine is a non-protein amino acid mainly extracted from green tea, it is the predominant amino acid in green tea. L-theanine is considered the main component responsible for the taste of green tea, L-theanine is a nutritional supplement for mood modulation. It inhibits glutamate transport into tumor cells, which causes decreased intracellular glutathione (GSH) levels.

KINGHERBS can offer 20% ~ 99% L-Theanine with very competitive prices. L-theanine may have activity in modulating the metabolism of cancer chemotherapeutic agents and ameliorating their side effects.


Functions:

The antioxidant activity; anti-cancer;

In the brain L-theanine increases dopamine and serotonin production;

L-theanine may counteract the stimulatory effect of caffeine;

L-theanine induces alpha-brain wave activity, which correlates with a perceived state of relaxation.

L-theanine helps curb a rising heart rate and blood pressure, and a few small human studies have found that it reduces anxiety;

L-theanine increases the activity of doxorubicin, idarubicin, pirarubicin, cisplatin, and irinotecan in tumor cells.


Side Effects and Toxicity:

L-theanine is generally well tolerated, and has an LD50 of greater than 5,000 mg/kg in rats. It is not mutagenic or carcinogenic in animals or bacteria.


Dosage and Administration:

For relaxation, 200 mg L-theanine can be taken 2-3 times daily. For cancer in conjunction with chemotherapy the dose is speculative, as no human studies have been performed. However, a dosage of 400-800 mg three times daily can be used safely.

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